Cohort study

Hospitalizations and Mortality Among Medicare Beneficiaries at Cardiovascular Risk

J Am Coll CardiolPublished

  • Retrospective cohort study

Authors' conclusion

In the later stages of the COVID-19 pandemic, among Medicare beneficiaries with CV risk factors or established CVD, hospitalizations were lower than before the pandemic, outpatient care was used more frequently, and mortality was significantly elevated across risk groups and geographies, with the greatest increases seen in vulnerable communities and those covered by Medicare Advantage.

Study context

Population
Medicare fee-for-service and Medicare Advantage beneficiaries with cardiovascular (CV) risk factors (hypertension, DM, hyperlipidemia) or cardiovascular disease (CVD) (CHD, HF, AF, stroke), 2018–2022
Participants
55,214,638 vs 51,355,577
Exposure
Late pandemic vs prepandemic period
  • Late pandemicn = 55,214,638
  • Prepandemicn = 51,355,577reference
Outcome
Acute care visits, outpatient visits and all-cause mortality (aIRR)

Main finding

As reported in the abstract

Adjusted incidence rate ratio (aIRR)

hospital visits
0.918 (95% CI 0.915–0.922)
outpatient visits
1.141 (95% CI 1.134–1.149)
all-cause mortality
1.248 (95% CI 1.240–1.257)

Observational data: associations, not effects.

Further findings

OutcomeaIRR (95% CI)
All-cause mortality, most socially vulnerable communities (subgroup)1.116 (1.106–1.124)
All-cause mortality, Medicare Advantage (subgroup)1.342 (1.329–1.356)

Original publication

Hospitalizations and Mortality Among Medicare Beneficiaries at Cardiovascular Risk. J Am Coll Cardiol. Published 21 January 2026. doi:10.1016/j.jacc.2025.11.033

Summarised from the published abstract; every number is checked against it