How to Facilitate Seamless Translation from Basic Concepts to New Heart Failure Drugs. A Scientific Statement of the Heart Failure Association of the ESC

Translation from basic research to new HF drugs: facilitating HF drug development, gaps ('valley of death') between critical steps, early validation and de-validation of new concepts ('rigorous translation'), forums for cross-talk between clinician-scientists, basic HF researchers, biotech and industry, and lessons from successes outside HF