Arrhythmias & electrophysiology
Hybrid Ablation Versus Repeated Catheter Ablation in Persistent Atrial Fibrillation: A Randomized Controlled Trial
Authors' conclusion
Hybrid AF ablation is an efficacious and safe procedure and results in better outcomes than catheter ablation for the treatment of patients with persistent AF.
Study context
- Population
- Ablation-naive patients with (long-standing) persistent atrial fibrillation (AF)
- Participants
- 41 patients
- Comparison
- Hybrid ablation vs catheter ablation
- Hybrid ablation (HA)n = 19
- Catheter ablation (CA)n = 22reference
- Primary endpoint
- Freedom from any atrial tachyarrhythmia >5 minutes off antiarrhythmic drugs
- Follow-up
- 12 months
Methodological detailsprospective, superiority, unblinded
- Prospective
- Superiority
- Unblinded
Primary result
As reported in the abstract
P = 0.002
Safety
| Outcome | HA | CA |
|---|---|---|
| Complications | ||
| Pericarditis requiring pericardiocentesis | 1 | — not stated in the abstract |
| Femoral arteriovenous fistula | 1 | — not stated in the abstract |
| Femoral artery bleeding | — not stated in the abstract | 1 |
— not stated in the abstract
- (Serious) adverse events · 21% vs 14%, comparable between groups
- P = 0.685
Complications
- No deaths, strokes, pacemaker implantations or conversions to sternotomy
Original publication
Hybrid Ablation Versus Repeated Catheter Ablation in Persistent Atrial Fibrillation: A Randomized Controlled Trial. JACC Clin Electrophysiol. Published 18 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →