Hyperacute T Waves Are Specific for Occlusion Myocardial Infarction, Even Without Diagnostic ST-Segment Elevation
Authors' conclusion
The HATW score is the first objective definition of HATW showing significant clinical utility as an ECG finding of acute coronary occlusion in potential acute coronary syndrome patients.
Study context
- Population
- Adults with possible ACS at five PCI centres; outcome MI with TIMI flow grade 0–1 culprit lesion618 excluded
- Participants
- 3,274 adults
- Comparison
- HATW score for acute coronary occlusion
- Outcome
- HATW score performance for acute coronary occlusion in patients without STEMI criteria
Methodological detailsretrospective, multicentre, derivation and validation groups, Derivation n = 1,261; validation n = 1,395
- Retrospective
- Multicentre
- Derivation and validation groups
- Derivation n = 1,261; validation n = 1,395
Performance
As reported in the abstract
Performance for acute coronary occlusion, patients without STEMI criteria (validation)
Specificity
98.4%
Sensitivity
20.7%
PPV
47.4%
Positive likelihood ratio
12.54
Further findings
Culprit lesion causing acute MI, no STEMI criteria but positive HATW score
- Had culprit lesion causing acute MI
- 84%
Original publication
Hyperacute T Waves Are Specific for Occlusion Myocardial Infarction, Even Without Diagnostic ST-Segment Elevation. JACC Adv. Published 31 August 2025. doi:10.
Summarised from the published abstract; every number is checked against it