Arrhythmias & electrophysiologyCohort study
Impact of atrial fibrillation ablation on biatrial strain: Differences between left and right atrial function
- retrospective analysis
Authors' conclusion
AF ablation led to significant biatrial functional recovery, with RA improvement exceeding that of LA. Both postprocedural LASr and RASr independently predicted AF/AT recurrence, supporting chamber-specific atrial strain as a sensitive marker of reverse remodeling and procedural outcome.
Study context
- Population
- Patients undergoing initial atrial fibrillation (AF) ablation who underwent pre- and postprocedural echocardiographypatients analyzed
- Participants
- 81 patients
- Exposure
- biatrial strain before and after AF ablation, LA vs right atria (RA), and its predictive value for AF/AT recurrence
Main finding
As reported in the abstract
LASr before to after ablation
15.3% ± 10.0% to 19.9% ± 8.2%
Observational data: associations, not effects.
Further findings
AF/AT recurrence, predictors
| Comparison | hazard ratio (95% CI) | P value | |
|---|---|---|---|
| Postprocedural LASr · independent predictor | 0.92 (0.85–1.0) | P = 0.049 | |
| Postprocedural RASr · independent predictor | 0.94 (0.89–0.99) | P = 0.016 | |
| 0.512Hazard ratio (log scale) |
| Outcome | Values | Estimate | P value |
|---|---|---|---|
| Change in reservoir strain (ΔRASr vs ΔLASr) · greater improvement in RASr than LASr | RA ΔRASr 9.0% ± 10.7% · LA ΔLASr 4.5% ± 8.4% | P < 0.001 | |
| Discrimination for AF/AT recurrence (ROC) · similar discriminative ability | LA area under the curve 0.75 · cutoff value 20.0% · RA area under the curve 0.69 · cutoff value 27.0% | P = 0.367 |
RA reservoir strain (RASr) · after AF ablation
- RASr before to after ablation
- 18.3% ± 10.8% to 27.3% ± 9.3%
- P < .001 for both
LA conduit strain
- did not change significantly
- −9.3% ± 5.6% to −10.3% ± 4.4%
- P = .071
RA conduit strain
- improved significantly
- −10.3% ± 6.3% to −14.1% ± 6.2%
- P < .001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Summarised from the published abstract; every number is checked against it