Acute cardiac care & resuscitationCohort study

Impact of cardiac arrest in patients with cardiogenic shock due to ST-elevation myocardial infarction

ResuscitationPublished

  • retrospective study
  • consecutive patients
  • two tertiary university hospitals

Authors' conclusion

In STEMI-related CS, concomitant OHCA or IHCA is associated with distinct clinical profiles, coronary anatomy, intensity of treatment and markedly impaired long-term survival.

Study context

Population
Patients with cardiogenic shock (CS) and ST-elevation myocardial infarction (STEMI) undergoing immediate coronary angiography and percutaneous coronary intervention (PCI), admitted between 2016 and 2025STEMI-CS-no CA 150 · STEMI-CS-OHCA 120 · STEMI-CS-IHCA 75
Participants
345 patients
Exposure
CS without cardiac arrest vs CS with OHCA vs CS with in-hospital cardiac arrest (IHCA)
  • STEMI-CS-no CAn = 150
  • STEMI-CS-OHCAn = 120
  • STEMI-CS-IHCAn = 75

Main finding

As reported in the abstract

Initial shockable rhythm

Observational data: associations, not effects.

Further findings

All-cause mortality · 1-year

OutcomeSTEMI-CS-no CASTEMI-CS-OHCASTEMI-CS-IHCA
Time to return of spontaneous circulationNot reported in the abstract19.6 min10.0 min
SYNTAX score18.621.527.2
  • Time to return of spontaneous circulation: p < 0.001
  • SYNTAX score: p < 0.001
  • All-cause mortality: STEMI-CS-OHCA p = 0.004
  • All-cause mortality: STEMI-CS-IHCA p < 0.001
  • All-cause mortality: no significant difference between cardiac arrest subgroups (p = 0.555)

Baseline characteristics of STEMI-CS-IHCA

STEMI-CS-IHCA patients were older
Lower arterial pressure, left ventricular ejection fraction, estimated glomerular filtration rate and higher arterial lactate in STEMI-CS-IHCA compared to STEMI-CS-no CA and STEMI-CS-OHCA

Original publication

Impact of cardiac arrest in patients with cardiogenic shock due to ST-elevation myocardial infarction. Resuscitation. Published 20 April 2026. doi:10.1016/j.resuscitation.2026.111094

Summarised from the published abstract; every number is checked against it