Valvular & structural heart diseaseCohort study
Impact of Coronary Artery Disease and Revascularization on Outcomes After Transcatheter Tricuspid Edge-to-Edge Repair
- Observational cohort study
- consecutive patients
Authors' conclusion
Obstructive CAD is common but typically low in complexity among T-TEER candidates. In low- and intermediate-risk patients, a higher residual SYNTAX score is associated with reduced survival.
Study context
- Population
- Patients undergoing tricuspid transcatheter edge-to-edge repair (T-TEER) with preprocedural coronary angiography and SYNTAX scoringconsecutive
- Participants
- 361 patients
- Exposure
- Obstructive coronary artery disease (CAD) vs no CAD
- CADn = 124
- Outcome
- All-cause mortality
- Follow-up
- 12 months
Main finding
As reported in the abstract
12-month all-cause mortality
P = 0.616
- Overall 12-month mortality
- 16.7%
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| 12-month mortality, elevated vs lower residual SYNTAX score, by TRI-SCORE risk (subgroup) · 12 months — Elevated residual SYNTAX vs No CAD · low/intermediate risk: 20.8% vs 6.4% · effect modification by TRI-SCORE procedural risk | P = 0.016 |
| 12-month mortality, elevated vs lower residual SYNTAX score, by TRI-SCORE risk (subgroup) · 12 months — Elevated residual SYNTAX vs No CAD · high risk: 27.6% vs 27.1% · effect modification by TRI-SCORE procedural risk | P = 0.927 |
- CAD prevalence and complexity
- 34.3% · 124 of 124
Risk stratification: residual SYNTAX added to TRI-SCORE (low/intermediate-risk CAD)
- ΔC
- +0.099
Original publication
Impact of Coronary Artery Disease and Revascularization on Outcomes After Transcatheter Tricuspid Edge-to-Edge Repair. JACC Cardiovasc Interv. Published 25 May 2026. doi:10.1016/j.jcin.2026.03.025
Summarised from the published abstract; every number is checked against it