Arrhythmias & electrophysiologyCohort study
Impact of Early Atrial Tachyarrhythmia Within the Blanking Period on Late Recurrence After Pulsed Field Ablation of Atrial Fibrillation
- prospective registry
- all consecutive patients
- single institution
Authors' conclusion
After PFA for AF, atrial tachyarrhythmias at any time within the first 3 months, regardless of timing or need for cardioversion, strongly predict late recurrence and warrant increased monitoring intensity in the early postablation period.
Study context
- Population
- Patients undergoing pulsed field ablation (PFA) for atrial fibrillation (AF) at our institution (Feb 2024- March 2025)patients followed for 1 year
- Participants
- 1,608 patients
- Exposure
- Early atrial tachyarrhythmias (ERAT) vs no ERAT
- ERATn = 334
Main finding
LRAT (recurrences after 90 days) · 1 year
Hazard ratio
4.89
95% CI 4.04–5.93
P < 0.001
By group
ERAT vs no ERAT
HR 4.89 (95% CI 4.04–5.93); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | ERAT | no ERAT | HR (95% CI) | P value | |
|---|---|---|---|---|---|
| Need for cardioversion · rates P < 0.001 | 25.1% | 7.2% | 1.49 (1.10–2.02) | P = 0.008 | |
| 0.512Hazard ratio (log scale) |
- LRAT by ERAT timing (≤30 vs 31-90 days): ERAT ≤30 days 70.4% · adjusted HR vs no ERAT 5.40
- LRAT by ERAT timing (≤30 vs 31-90 days): ERAT 31-90 days 65.5% · adjusted HR vs no ERAT 4.34
- LRAT by ERAT timing (≤30 vs 31-90 days): P = 0.41
- LRAT by ERAT timing (≤60 vs 61-90 days): ERAT ≤60 days 68.6% · adjusted HR vs no ERAT 4.91
- LRAT by ERAT timing (≤60 vs 61-90 days): ERAT 61-90 days 67.1% · adjusted HR vs no ERAT 4.83
- LRAT by ERAT timing (≤60 vs 61-90 days): P = 0.88
- LRAT in ERAT patients with or without cardioversion (secondary analysis): ERAT with cardioversion 73%
- LRAT in ERAT patients with or without cardioversion (secondary analysis): ERAT without cardioversion 66.7%
- LRAT in ERAT patients with or without cardioversion (secondary analysis): P = 0.29
- LRAT in ERAT patients with or without cardioversion (secondary analysis): Interaction testing: no significant differences across ERAT-timing or cardioversion subgroups (all P > 0.05)
Original publication
Impact of Early Atrial Tachyarrhythmia Within the Blanking Period on Late Recurrence After Pulsed Field Ablation of Atrial Fibrillation. JACC Clin Electrophysiol. Published 23 September 2026. doi:10.1016/j.jacep.2026.08.024
Summarised from the published abstract; every number is checked against it