Arrhythmias & electrophysiology
Impact of Left Atrial Posterior Wall Ablation During Pulsed-Field Ablation for Persistent Atrial Fibrillation
Authors' conclusion
In patients with PersAF undergoing PFA, as compared to PVI-alone, adjunctive LAPW ablation did not improve freedom from atrial arrhythmia at 12 months.
Study context
- Population
- Consecutive patients with persistent AF undergoing post-approval pulsed-field ablation (PFA) with a pentaspline catheter
- Participants
- 547 patients
- Exposure
- Pulmonary vein isolation (PVI) + left atrial posterior wall (LAPW) ablation vs PVI alone with PFA
- PVI + LAPWn = 131
- Outcome
- Freedom from any atrial arrhythmia ≥30 seconds
- Follow-up
- 1 year
Methodological detailsconsecutive patients, propensity-matched cohort
- Consecutive patients
- Propensity-matched cohort
Main finding
As reported in the abstract
Freedom from atrial arrhythmias (Kaplan-Meier estimate), full cohort
P = 0.68
Observational data: associations, not effects.
Further findings
Freedom from atrial arrhythmias, propensity-matched cohort · 1 year · matched cohort
P = 0.34
Safety
Major adverse events (acute and chronic composite) · no significant difference
P = 0.51
Original publication
Impact of Left Atrial Posterior Wall Ablation During Pulsed-Field Ablation for Persistent Atrial Fibrillation. JACC Clin Electrophysiol. Published 31 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →