Impact of Left Ventricular to Mitral Valve Ring Mismatch on Recurrent Ischemic Mitral Regurgitation After Ring Annuloplasty

CirculationPublished Secondary analysis of the Cardiothoracic Surgical Trials Network ischemic mitral regurgitation (IMR) randomised trials

Primary result · Moderate or greater MR (recurrence)Result — go to the resultOdds ratio 2.20 95% CI 1.05–4.62

Authors' conclusion

LV-MV ring size mismatch is associated with increased risk of MR recurrence.

Study context

Population
Patients with moderate or severe ischemic MR who received mitral valve (MV) repair (restrictive ring annuloplasty)
Participants
214 patients
Comparison
LV-MV ring mismatch and recurrent MR
Primary endpoint
Recurrent MR (moderate or greater)
Follow-up
1 year after surgery

Primary result

Moderate or greater MR (recurrence) · 1 year

Odds ratio

2.20

95% CI 1.05–4.62

P = 0.038

LVESd/ring size (per 0.5 increase)
OR 2.20 (95% CI 1.05–4.62); P = 0.038

Per 0.5 increase, as printed

As reported in the abstract

Patients with moderate or greater MR at 1 year
45 of 214 (21%)
Univariable: larger LV end-systolic dimension (LVESd) associated with recurrent MR
P = 0.02
Univariable: LVESd/ring size associated with recurrent MR
P = 0.007

Original publication

Impact of Left Ventricular to Mitral Valve Ring Mismatch on Recurrent Ischemic Mitral Regurgitation After Ring Annuloplasty. Circulation. Published 25 October 2016. doi:10.1161/circulationaha.115.021014

Summarised from the published abstract; every number is checked against it

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