Impact of multisite artery disease on clinical outcomes after percutaneous coronary intervention: an analysis from the e-Ultimaster registry
Authors' conclusion
Patients with previously known vascular disease experienced an increased risk of adverse cardiovascular events and mortality post-PCI. This risk is highest among patients with multisite artery disease.
Study context
- Population
- Patients undergoing percutaneous coronary intervention (PCI) in the e-Ultimaster study
- Participants
- 37,198 patients
- Comparison
- Multisite artery disease vs single-territory vascular disease vs no known prior vascular disease
- Primary endpoint
- Coronary target lesion failure:
- Cardiac death
- Target vessel-related MI
- Clinically driven target lesion revascularization
- Follow-up
- 1 year
Methodological detailsinverse propensity score weighted
- Inverse propensity score weighted
Primary result
As reported in the abstract
TLF
- Target lesion failure (TLF) rate incrementally increased with number of diseased vascular beds
- P < 0.01 for all comparisons
Further findings
All-cause death · after IPSW
Cardiac mortality · after IPSW
Distribution of groups
- All-cause death — Incremental increase
- P < 0.01 for all comparisons
- Cardiac mortality — Incremental increase
- P ≤ 0.01 for all comparisons
Original publication
Impact of multisite artery disease on clinical outcomes after percutaneous coronary intervention: an analysis from the e-Ultimaster registry. Eur Heart J Qual Care Clin Outcomes. Published 25 July 2022. doi:10.
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