Impact of Myocardial Bridges on Long-Term Outcomes After Left Anterior Descending Chronic Total Occlusion Recanalization
Authors' conclusion
MBs are prevalent after LAD CTO recanalization. Although their presence is associated with adverse outcomes, the risk is driven mainly by stent extension into the bridged segment.
Study context
- Population
- Patients with LAD chronic total occlusion undergoing intravascular ultrasound-guided PCI, January 2019 to December 2021analysed
- Participants
- 685 patients
- Exposure
- Myocardial bridge vs no myocardial bridge
- Outcome
- Major adverse cardiac events (MACE):
- Cardiac death
- Spontaneous MI
- Ischemia-driven revascularization
- Follow-up
- 5 years
Methodological detailsconsecutive patients, IVUS-guided PCI
- Consecutive patients
- IVUS-guided PCI
Main finding
As reported in the abstract
MACE · median 5-year follow-up
P = 0.006
Observational data: associations, not effects.
Further findings
| Outcome | Values | P value |
|---|---|---|
| Ischemia-driven revascularization · median 5-year follow-upMB vs No MB | MB 15.1% · No MB 7.9% | P = 0.004 |
| MACE, by stent extension into the MB (subgroup) · median 5-year follow-upStent extension into MB vs MB spared · stent extension in 174 of 393 with MB (44.3%) | Stent extension into MB 21.4% · MB spared 11.9% | P = 0.0017 |
| MACE, MB spared from stenting vs no MB (subgroup) · median 5-year follow-up | MB spared 11.9% | P = 0.25 |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Impact of Myocardial Bridges on Long-Term Outcomes After Left Anterior Descending Chronic Total Occlusion Recanalization. JACC Cardiovasc Interv. Published 24 August 2026. doi:10.
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