Coronary disease & ACSCohort study

Impact of Myocardial Bridges on Long-Term Outcomes After Left Anterior Descending Chronic Total Occlusion Recanalization

JACC Cardiovasc IntervPublished

  • Retrospective cohort study
  • consecutive patients
  • IVUS-guided PCI

Authors' conclusion

MBs are prevalent after LAD CTO recanalization. Although their presence is associated with adverse outcomes, the risk is driven mainly by stent extension into the bridged segment.

Study context

Population
Patients with LAD chronic total occlusion undergoing intravascular ultrasound-guided PCI, January 2019 to December 2021analysed
Participants
685 patients
Exposure
Myocardial bridge vs no myocardial bridge
Outcome
Major adverse cardiac events (MACE):
  • Cardiac death
  • Spontaneous MI
  • Ischemia-driven revascularization
Follow-up
5 years

Main finding

As reported in the abstract

MACE · median 5-year follow-up

P = 0.006

Observational data: associations, not effects.

Further findings

OutcomeValuesP value
Ischemia-driven revascularization · median 5-year follow-upMB 15.1% · No MB 7.9%P = 0.004
MACE, by stent extension into the MB (subgroup) · median 5-year follow-up · stent extension in 174 of 393 with MB (44.3%)Stent extension into MB 21.4% · MB spared 11.9%P = 0.0017
MACE, MB spared from stenting vs no MB (subgroup) · median 5-year follow-upMB spared 11.9%P = 0.25

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Impact of Myocardial Bridges on Long-Term Outcomes After Left Anterior Descending Chronic Total Occlusion Recanalization. JACC Cardiovasc Interv. Published 24 August 2026. doi:10.1016/j.jcin.2026.06.020

Summarised from the published abstract; every number is checked against it