Impact of myocardial perfusion and coronary calcium on medical management for coronary artery disease
Authors' conclusion
Abnormal MPI testing was associated with significant changes in medical therapy. Both calcium burden and perfusion abnormalities were associated with increased prescriptions of medical therapy for CAD.
Study context
- Population
- Consecutive patients undergoing single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) with computed tomography (CT) attenuation correction, 2015–2021
- Participants
- 9,908 patients
- Exposure
- Abnormal vs normal perfusion; extensive CAC vs no calcium
- Outcome
- Change in ASA and statin prescription
- Follow-up
- Within 180 days after the test
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
Increase in statin prescription · within 180 days
Abnormal perfusion vs Normal perfusion: P < 0.001 · Extensive CAC vs No calcium: P < 0.001
Observational data: associations, not effects.
Original publication
Impact of myocardial perfusion and coronary calcium on medical management for coronary artery disease. Eur Heart J Cardiovasc Imaging. Published 27 October 2023. doi:10.
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