Prevention & lipidsMeta-analysis
Impact of neighbourhood and environmental factors on the risk of incident cardiovascular disease: a systematic review and meta-analysis
- Systematic review and meta-analysis of cohort studies
- random-effects
39 studies in systematic review; searches to 20th October 2024
Authors' conclusion
Our findings indicate a modest yet significant increase in CVD risk associated with elevated levels of air pollution, road noise, and neighbourhood deprivation
Study context
- Population
- Large cohort studies of neighbourhood exposures (retail environment, health services, physical environment, pollution, neighbourhood deprivation) and incident cardiovascular disease (CVD)28 studies in meta-analysis
- Participants
- over 41 million participants
- Comparison
- Higher vs lower neighbourhood and environmental exposures
- Outcome
- Incident (first-time) CVD
Pooled result
As reported in the abstract
Incident CVD
Estimate (95% CI)
PM2.5per 10 µg/m³ increase
HR 1.16(1.09–1.24)
NO2per 10 ppb increase
HR 1.05(1.02–1.07)
Road traffic noiseper 10 dB increase
RR 1.03(1.02–1.05)
High neighbourhood-level deprivation vs Low
RR 1.24(1.17–1.31)
Original publication
Impact of neighbourhood and environmental factors on the risk of incident cardiovascular disease: a systematic review and meta-analysis. Eur J Prev Cardiol. Published 19 March 2025. doi:10.1093/eurjpc/zwaf165
Summarised from the published abstract; every number is checked against it