Heart failure & cardiomyopathies
Impact of Pharmacist Telehealth Comanagement for Heart Failure: A Nonrandomized Controlled Study
Authors' conclusion
A dedicated pharmacist comanagement telehealth program for patients with HFrEF proved effective at improving GDMT use and reducing cardiac hospitalizations.
Study context
- Population
- In-network Medicare recipients with a heart failure with reduced ejection fraction (HFrEF) diagnosis (based on chart review)190 intervention and 277 comparison group patients · intervention 190 · comparison 277
- Participants
- 190 vs 277
- Comparison
- Intervention group vs comparison group
- Intervention groupn = 190
- Comparison groupn = 277reference
- Outcome
- Hospitalizations and achievement of target GDMT therapy
Methodological detailsdifference-in-difference analysis with inverse propensity weighting, integrated health care network, 2022 to 2023
- Difference-in-difference analysis with inverse propensity weighting
- Integrated health care network
- 2022 to 2023
Main finding
As reported in the abstract
intervention group vs comparison groupEstimate (95% CI)P value
Cardiac hospitalization
relative risk 0.26(0.08–0.86)
P = 0.026Achieving 3+ GDMT classes
OR 2.73(1.91–3.87)
P < 0.001Achieving 4 GDMT classes
OR 2.27(1.29–4.01)
P = 0.005- Adjusted absolute risk reduction of cardiac hospitalizations
- 14.2 hospitalizations per 100 patient-years
- Adjusted absolute increase in patients on 3+ guideline-directed medical therapy (GDMT) classes
- 23%
- Adjusted absolute increase in patients on 4 GDMT classes
- 21%
Original publication
Impact of Pharmacist Telehealth Comanagement for Heart Failure: A Nonrandomized Controlled Study. JACC Adv. Published 25 June 2025. doi:10.
Summarised from the published abstract; every number is checked against it