Valvular & structural heart disease
Impact of prolonged balloon inflation on valve expansion and early clinical outcomes following contemporary balloon-expandable transcatheter aortic valve implantation
- single-centre study
- consecutive patients
+1 more
- consecutive patients
Authors' conclusion
Prolonged balloon inflation during BE THV deployment is associated with favourable valve expansion, haemodynamic results, and a favourable safety profile, consistent with values reported in double-tap series. If confirmed in larger studies, this strategy may represent a simple alternative to routine double-tap in selected patients.
Study context
- Population
- Transcatheter aortic valve implantation (TAVI) patients treated for native tricuspid aortic stenosis with the SAPIEN 3 Ultra RESILIA THV using a prolonged balloon inflation strategy (8 seconds)mean age 78.8 years, 58% male, median Society of Thoracic Surgeons Predicted Risk of Mortality score 3.9%
- Participants
- 84 patients
- Comparison
- Valve expansion compared with three validated reference standards; results descriptively compared with previously published data on the double-tap technique
- Prolonged balloon inflationn = 84
Main finding
As reported in the abstract
THV expansion (manufacturer-defined nominal values as reference)
Mild underexpansion at the midframe level
98.5±1.3%
Further findings
| Outcome | Values |
|---|---|
| Mean gradient · 30 days | Prolonged balloon inflation mean 9.2 (IQR 7.0–10.3) mmHg |
Expansion vs previously published double-tap data
- 23, 26, and 29 mm valves: consistently similar or higher expansion
- 20 mm size: lower expansion
- Descriptive comparison
Device success
- Device success achieved in all cases
Moderate or severe paravalvular leak · 30 days
- No patients having moderate or severe paravalvular leak
Safety
| Outcome | Values |
|---|---|
| Permanent pacemaker implantation | Prolonged balloon inflation 6% |
Stroke · 30 days
- No stroke at 30 days
Original publication
Impact of prolonged balloon inflation on valve expansion and early clinical outcomes following contemporary balloon-expandable transcatheter aortic valve implantation. EuroIntervention. Published 15 October 2026. doi:10.
Summarised from the published abstract; every number is checked against it