Cohort study
Impact of remnant cholesterol on cardiovascular outcomes in non-myocardial infarction patients undergoing percutaneous coronary intervention
- Retrospective cohort study
- single-centre
Authors' conclusion
While RC did not associate with the composite MACE endpoint, higher concentrations of this subtype of triglyceride-rich lipoproteins was a marker for incident ischemic endpoints such as MI in patients undergoing PCI for a non-MI.
Study context
- Population
- Patients undergoing percutaneous coronary intervention (PCI) for a non-MI at a tertiary center, 2012–2023
- Participants
- 19,289 patients
- Exposure
- Remnant cholesterol (RC) percentile categories
- Outcome
- MACE:
- All-cause mortality
- Spontaneous MI
- Stroke
- Follow-up
- 1 year after PCI
Main finding
As reported in the abstract
MACE · 1 year
- Major adverse cardiovascular event (MACE) rates did not differ significantly according to RC concentrations
Observational data: associations, not effects.
Further findings
| Outcome | adjusted HR (95% CI) | P value | |
|---|---|---|---|
| Incident MI · trend p-value | 1.54 (1.07–2.22) | P = 0.010 | |
| 0.512Adjusted hazard ratio (log scale) |
Original publication
Impact of remnant cholesterol on cardiovascular outcomes in non-myocardial infarction patients undergoing percutaneous coronary intervention. Eur J Prev Cardiol. Published 22 October 2025. doi:10.1093/eurjpc/zwaf683
Summarised from the published abstract; every number is checked against it