Acute cardiac care & resuscitation
Impact of resuscitation duration on 12-month functional recovery following out-of-hospital cardiac arrest with initially shockable rhythms
Main finding · Favourable functional recovery, per minute increase in CPR duration (all patients)Result — go to the resultAdjusted odds ratio 0.905 95 % CI 0.899–0.911Authors' conclusion
In OHCA with an initially shockable rhythm, increasing CPR duration is associated with poorer long-term functional recovery and quality-of-life.
Study context
- Population
- Adults with emergency medical service (EMS)-attempted resuscitation for OHCA with initially shockable rhythm, 2015–2024 (excluding traumatic aetiology and EMS-witnessed OHCA)1,429 responded to follow-up
- Participants
- 6,371 adults
- Exposure
- Cardiopulmonary resuscitation (CPR) duration
- Outcome
- Favourable functional recovery (Glasgow Outcome Scale-Extended) and HRQoL
- Follow-up
- 12 months post-arrest
Main finding
As reported in the abstract
Favourable functional recovery, per minute increase in CPR duration (all patients) · 12 months
Adjusted odds ratio
0.905
95 % CI 0.899–0.911
Each minute increase in CPR duration
AOR 0.905 (95 % CI 0.899–0.911)
Each minute increase in CPR duration, as printed
Observational data: associations, not effects.
Further findings
| Outcome | AOR (95 % CI) | |
|---|---|---|
| Favourable recovery, per minute increase in CPR duration (12-month responders only) | 0.989 (0.980–0.998) | |
| 0.512Adjusted odds ratio (log scale) |
- Favourable recovery, per minute increase in CPR duration (12-month responders only): also associated with lower odds of living at home without care
Survival
- Survived to hospital discharge
- 2054 (32.6 %)
- Confirmed alive at 12 months (of discharged survivors)
- 1769 (86.1 %)
CPR duration among 12-month survivors with favourable functional recovery
min
- 50th percentile
- 8
- 90th percentile
- 25
- 99th percentile
- 69
Original publication
Impact of resuscitation duration on 12-month functional recovery following out-of-hospital cardiac arrest with initially shockable rhythms. Resuscitation. Published 12 September 2025. doi:10.
Summarised from the published abstract; every number is checked against it