Impact of sex on outcomes associated with polyvascular disease in patients after percutaneous coronary intervention (PCI)
Authors' conclusion
Women and men derive similar excess risk of MACE from PVD after PCI.
Study context
- Population
- Patients undergoing PCI at a tertiary-care centre, 2012–20195,467 women
- Participants
- 18,721 patients
- Exposure
- Polyvascular disease (PVD) vs coronary artery disease (CAD) alone, by sex
- Outcome
- Major adverse cardiovascular events (MACE):
- All-cause death
- MI
- Stroke
- Follow-up
- 1 year
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Women with PVD vs Women with CAD alone
Estimate (95% CI)P value
Adjusted hazard ratiowomen
1.54(1.20–1.99)
P < 0.001Men with PVD vs Men with CAD alone
Estimate (95% CI)P value
Adjusted hazard ratiomen
1.31(1.06–1.62)
P = 0.014Observational data: associations, not effects.
Further findings
PVD prevalence
P < 0.001
Original publication
Impact of sex on outcomes associated with polyvascular disease in patients after PCI. Am Heart J. Published 8 August 2024. doi:10. 1016/ j. ahj. 2024. 08. 002
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