Arrhythmias & electrophysiologyCohort study
Impact of timing of treatment for cardiac implantable electronic device infections on healthcare utilization and expenditures
- Retrospective cohort study
- multivariable adjustment
Authors' conclusion
Extraction was associated with lower hospitalization and lower healthcare expenditures in the year following CIED infection management period. Early extraction was associated with optimal healthcare utilization and expenditures.
Study context
- Population
- Medicare fee-for-service patients with a de novo cardiovascular implantable electronic device (CIED) implant and CIED infection >12 months after implant, 2006–2019
- Participants
- 9,594 patients
- Exposure
- Timing of CIED extraction vs no extraction within 30 days
- No extraction within 30 daysn = 7,819reference
- Extraction <7 daysn = 1,277
- Extraction 7–30 daysn = 498
- Outcome
- Healthcare utilization (all-cause hospitalization) and expenditures
Main finding
All-cause hospitalization in follow-up
Adjusted hazard ratio
0.79
95% CI 0.72–0.85
P < 0.001
Extraction <7 days vs No extraction within 30 days
adjusted HR 0.79 (95% CI 0.72–0.85); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | No extraction within 30 days | Extraction <7 days | Extraction 7–30 days |
|---|---|---|---|
| Healthcare expenditures · year following CIED infection | median $63 425 (IQR $22,853, $120 273) | median $36 824 (IQR $12,748, $77 772) | Not reported in the abstract |
Original publication
Impact of timing of treatment for cardiac implantable electronic device infections on healthcare utilization and expenditures. Europace. Published 29 August 2025. doi:10.1093/europace/euaf146
Summarised from the published abstract; every number is checked against it