Aortic & peripheral vascular disease
Improving 1-Year Outcomes of Infrainguinal Limb Revascularization: Population-Based Cohort Study of 104 000 Patients in England
Authors' conclusion
Our findings show that from 2006 to 2015, the overall survival increased and the risk of major lower limb amputation decreased following revascularization.
Study context
- Population
- Patients undergoing lower limb revascularization for infrainguinal PAD in England, January 2006 to December 2015 (Hospital Episode Statistics)
- Participants
- 103,934 patients
- Exposure
- Revascularization outcomes 2006-2007 vs 2014-2015, by endovascular or surgical procedure
- Outcome
- Major lower limb amputation and death (cumulative incidence, adjusted)
- Follow-up
- 1 year after revascularization
Methodological detailsnational administrative database, competing risks regression
- National administrative database
- Competing risks regression
Main finding
As reported in the abstract
Estimated 1-year risk of major amputation
2006-2007
2014-2015
Observational data: associations, not effects.
Further findings
Amputation and death trends by indication
- Trends observed for all indication categories; largest reductions in severe limb ischemia with ulceration or gangrene
Patient profile over study period
- Morbidity increased; larger proportion treated for severe PAD using less invasive procedures
Original publication
Improving 1-Year Outcomes of Infrainguinal Limb Revascularization: Population-Based Cohort Study of 104 000 Patients in England. Circulation. Published 9 January 2018. doi:10.
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