Acute cardiac care & resuscitationCohort study
In-Hospital and Long-Term Outcomes of Cardiogenic Shock Complicating Myocardial Infarction Versus Heart Failure
- Retrospective cohort study
- population-based
- nationwide
Authors' conclusion
With medical advances during the past 10 years, the mortality of CS has decreased significantly, but the mortality of HF-CS remains high.
Study context
- Population
- Adults (≥18 years) with cardiogenic shock admitted to an ICU, Korean National Health Insurance Service database, 2010–2020
- Participants
- 136,092 adults
- Exposure
- HF-CS vs AMI-CS
- HF-CSn = 87,388
- AMI-CSn = 48,704reference
- Outcome
- In-hospital mortality
Main finding
As reported in the abstract
Adjusted odds ratio
1.47
95% CI 1.43–1.52
By group
HF-CS vs AMI-CS
adjusted OR 1.47 (95% CI 1.43–1.52)
Observational data: associations, not effects.
Secondary outcomes
| Outcome | AMI-CS | HF-CS | Estimate | |
|---|---|---|---|---|
| Cardiac replacement therapy (LV assist device implantation or heart transplantation) | adjusted OR 1.65 (95% CI 1.16–2.34) | |||
| Follow-up mortality after successful discharge | 8.5% | 19.3% | adjusted HR 1.54 (95% CI 1.48–1.59) | |
| 0.512Ratio (log scale) |
| Outcome | adjusted ratio (95% CI) |
|---|---|
| In-hospital medical costs | 0.79 (0.79–0.80) |
Trends over the 10-year study period
- In-hospital mortality rate decreased and actual medical costs tended to increase, regardless of cardiogenic shock (CS) aetiology
Original publication
In-Hospital and Long-Term Outcomes of Cardiogenic Shock Complicating Myocardial Infarction Versus Heart Failure. Eur J Heart Fail. Published 10 June 2024. doi:10.1002/ejhf.3333
Summarised from the published abstract; every number is checked against it