Acute cardiac care & resuscitationCase-control study

Incidence, analysis and risk of out-of-hospital cardiac arrest in individuals with non-ischaemic dilated cardiomyopathy

ESC Heart FailPublished

  • observational, register-based study with cohort and nested case-control analyses
  • nationwide
  • exposure-matched cohort

Authors' conclusion

The Danish NIDCM population has a significantly increased incidence of OHCA compared to the general population but a comparable mortality despite multiple positive resuscitation characteristics.

Study context

Population
Individuals with non-ischaemic dilated cardiomyopathy (NIDCM) and the general population, Denmark's healthcare registers, 1 June 2001 to 31 December 2022
Comparison
NIDCM patients compared with the general population

Main finding

As reported in the abstract

Incidence rate of OHCA

Observational data: associations, not effects.

Further findings

Risk of OHCA, de novo NIDCM vs non-NIDCM · 5 and 10 years · Aalen-Johansen estimator in an exposure-matched cohort

Male, 5-year

Male, 10-year

Female, 5-year NIDCM 1.4% · non-NIDCM 0.4

Female, 10-year

Initial shockable rhythm among OHCAs · higher with NIDCM · nested case-control study

P < 0.001

Mortality after OHCA · 30 day and 1-year

30 day

1-year NIDCM 82% · non-NIDCM 84

Mortality after OHCA · 30 day and 1-year

No significant differences

Original publication

Incidence, analysis and risk of out-of-hospital cardiac arrest in individuals with non-ischaemic dilated cardiomyopathy. ESC Heart Fail. Published 31 July 2026. doi:10.1093/eschf/xvag207

Summarised from the published abstract; every number is checked against it