Acute cardiac care & resuscitationCohort study
Incidence, implications, and management of sense-B-noise failure in subcutaneous cardioverter-defibrillator patients: insights from a large multicentre registry
- Retrospective multicentre registry study
- nine centres in Europe and the US
Data from medical records, device telemetry and manufacturer reports
Authors' conclusion
This multicentre analysis' findings shed light on a rare but clinically highly significant adverse event in S-ICD therapy.
Study context
- Population
- Patients implanted with S-ICD models 1010, A209 and A219, October 2009–July 2023
- Participants
- 1,158 patients
- Outcome
- Incidence and implications of sense-B-noise events
Main finding
As reported in the abstract
Sense-B-noise failure · median follow-up 46 (IQR 23-64) months
- Patients with sense-B-noise failure
- 6
- Proportion of all patients
- 0.5%
- Proportion of all inappropriate shocks (IAS)
- 5.6%
- Diagnosed after an IAS episode
- 6
- Median lead dwell time in affected patients (months)
- 23 (2-70)
Observational data: associations, not effects.
Further findings
Inappropriate shocks (≥1 IAS)
- Patients with ≥1 IAS
- 107 (9.2%)
Management of sense-B-noise
- Reprogramming to secondary vector
- 3
- System removal and S-ICD reimplantation (low secondary-vector amplitude)
- 2
- Secondary vector, then system exchange for T-wave-oversensing IAS
- 1
Original publication
Incidence, implications, and management of sense-B-noise failure in subcutaneous cardioverter-defibrillator patients: insights from a large multicentre registry. Europace. Published 11 June 2024. doi:10.1093/europace/euae161
Summarised from the published abstract; every number is checked against it