Cohort study
Incidence of 12 common cardiovascular diseases and subsequent mortality risk in the general population
- Cohort study
- England-wide linked electronic health records
- CVD as time-varying exposures
Authors' conclusion
Incident events of 12 common CVD show significant adverse and markedly differential associations with subsequent cardiovascular, non-cardiovascular, and all-cause mortality risk in the general population.
Study context
- Population
- People ≥30 years of age initially free of CVD, England, 2010–16
- Participants
- 1,310,518 people
- Exposure
- Incident non-fatal events of 12 common cardiovascular diseases (CVDs) vs no CVD event
- Outcome
- Cardiovascular, non-cardiovascular and all-cause mortality
- Follow-up
- Median 4.2 years
Main finding
As reported in the abstract
Cardiovascular, non-cardiovascular and all-cause mortality after incident CVD (12 CVDs as time-varying exposures)
HRR
- stable angina · cardiovascular mortality; lowest of the 12 CVDs
- 1.67 (95% CI 1.47–1.89)
- haemorrhagic stroke · cardiovascular mortality; highest of the 12 CVDs
- 7.85 (95% CI 6.62–9.31)
- transient ischaemic attack · non-cardiovascular mortality; lowest of the 12 CVDs
- 1.10 (95% CI 1.00–1.22)
- sudden cardiac arrest · non-cardiovascular mortality; highest of the 12 CVDs
- 4.55 (95% CI 4.03–5.13)
- transient ischaemic attack · all-cause mortality; lowest of the 12 CVDs
- 1.24 (95% CI 1.13–1.35)
- sudden cardiac arrest · all-cause mortality; highest of the 12 CVDs
- 4.92 (95% CI 4.44–5.46)
Observational data: associations, not effects.
Original publication
Incidence of 12 common cardiovascular diseases and subsequent mortality risk in the general population. Eur J Prev Cardiol. Published 9 June 2023. doi:10.1093/eurjpc/zwad192
Summarised from the published abstract; every number is checked against it