Arrhythmias & electrophysiologyCohort study
Incidence of atrial fibrillation in pacemaker patients with left bundle branch area pacing vs right ventricular pacing leads
- Propensity score-matched comparison in the LATITUDE remote monitoring database
- exact match on percent right ventricular (RV) pacing group
- landmark analysis
Authors' conclusion
LBBAP was associated with a lower incidence of new-onset AF than RVP in pacemaker patients with a high pacing burden.
Study context
- Population
- Dual-chamber pacemaker patients without prior atrial fibrillation (AF) with left bundle branch area pacing (LBBAP) or right ventricular pacing (RVP) leads in the RV portpropensity-matched patients, leads identified: RVP N = 5225, LBBAP N = 4970 · LBBAP 3,943 · RVP 3,943
- Participants
- 7,886 patients
- Exposure
- LBBAP vs RVP
- LBBAPn = 3,943
- RVPn = 3,943
Main finding
As reported in the abstract
Patients with 24-hour AF · 21 months of follow-up
P = 0.037
Observational data: associations, not effects.
Further findings
24-hour AF stratified by percent RV pacing ≥ or <40%
- 24-hour AF stratified by percent RV pacing ≥ or <40% — RVP group had significantly more 24-hour AF when percent pacing was ≥ 40%
- P = .004
Propensity match characteristics
- not significantly different between the groups
Original publication
Incidence of atrial fibrillation in pacemaker patients with left bundle branch area pacing vs right ventricular pacing leads. Heart Rhythm. Published 28 August 2026. doi:10.1016/j.hrthm.2026.08.039
Summarised from the published abstract; every number is checked against it