Heart failure & cardiomyopathiesMeta-analysis
Incidence of Cardiac Arrhythmias Identified by Insertable Cardiac Monitors in Patients With Symptomatic Heart Failure
- Pooled analysis of prospective cohort studies
- LINQ-HF and Phase 1 ALLEVIATE-HF studies
- AI adjudication then manual verification
Authors' conclusion
In CHF patients undergoing ambulatory, continuous, accurate arrhythmia monitoring, the incidence of AF and bradycardia/pause events was high and similar in HFpEF vs HFrEF patients. VT/VF was lower in HFpEF than HFrEF, but clinically important.
Study context
- Population
- Chronic heart failure (CHF) patients with recent HF events, not indicated for cardiac implantable electronic devices, implanted with an insertable cardiac monitor49.1% ejection fraction (EF) ≥50%
- Participants
- 163 patients
- Comparison
- Heart failure with reduced ejection fraction (HFrEF) vs heart failure with preserved ejection fraction (HFpEF)
- Outcome
- Occurrence of cardiac arrhythmias (AF, VT/VF, bradycardia/pauses)
Pooled result
As reported in the abstract
Cardiac arrhythmias
AF occurrence
AF incidence without prior AF
Bradycardia or pause
VT/VF
- Atrial fibrillation (AF) occurrence overall at 2 years
- 59.7%
- AF incidence without prior AF, overall
- 23.8%
- Bradycardia or pause, overall
- 37.2%
- Bradycardia or pause during daytime
- 30.3%
- Bradycardia or pause during nighttime
- 19.4%
- Ventricular tachycardia (VT)/VF, overall
- 14.3%
Original publication
Incidence of Cardiac Arrhythmias Identified by Insertable Cardiac Monitors in Patients With Symptomatic Heart Failure. JACC Heart Fail. Published 1 July 2025. doi:10.1016/j.jchf.2025.102527
Summarised from the published abstract; every number is checked against it