Arrhythmias & electrophysiology

Incidence of clinical atrial fibrillation and related complications using a screening algorithm at a nationwide level

EuropacePublished Retrospective cohort study

Authors' conclusion

These findings at a nationwide scale confirm the relevance of the subgroups in the EHRA algorithm for identifying a higher risk of AF incidence, showing that older patients (>75 years, regardless of comorbidities) have a higher incidence of AF than those with prior ischaemic stroke.

Study context

Population
Patients hospitalized in France in 2012 without a history of atrial fibrillation (AF), with ≥5-year follow-up (FU) (or earlier death)mean age 58.9 y, 64.5% women
Participants
4,526 104 patients
Exposure
AF incidence across European Heart Rhythm Association (EHRA) screening algorithm risk groups
Outcome
Yearly incidence of AF
Follow-up
At least 5-year FU
Methodological detailsnationwide, French administrative hospital discharge database
  • Nationwide
  • French administrative hospital discharge database

Main finding

As reported in the abstract

Yearly AF incidence by EHRA risk group

Group 1

4.58% per year

Group 2

6.21% per year

Group 3a

3.50% per year

Group 3b

2.01% per year

Group 4a

1.23% per year

Group 4b

0.35% per year

Patients with incident AF during FU
327 012
Yearly AF incidence, overall population
1.86%

Observational data: associations, not effects.

Further findings

Annual AF incidence by number of comorbidities, age < 65 y

No comorbidities
0.35%
Eight comorbidities
9.08%
  • Increased progressively with number of comorbidities

Annual AF incidence by number of comorbidities, age 65-75 y

No comorbidities
2.01%
Eight comorbidities
11.47%
  • Same increasing trend

Original publication

Incidence of clinical atrial fibrillation and related complications using a screening algorithm at a nationwide level. Europace. Published 20 March 2023. doi:10.1093/europace/euad063

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