Cohort study

Incident heart failure and recurrent coronary events following acute myocardial infarction

Eur Heart JPublished

  • Retrospective cohort study
  • multicentre
  • landmark analysis at 3 months post-discharge

Authors' conclusion

In a contemporary post-MI cohort, the risk for incident HF was greater than recurrent MI, even among those with normal EF and no HF at discharge.

Study context

Population
Patients with a primary discharge diagnosis of myocardial infarction (MI) at 28 Baylor Scott & White Health hospitals, January 2015 to December 2021landmark cohort N = 6210
Participants
6,804 patients
Outcome
Incident HF, recurrent MI, all-cause death, all-cause and CV rehospitalizations
Follow-up
1 year (landmark at 3 months post-discharge)

Main finding

As reported in the abstract

1-year outcomes (landmark cohort) · 1 year
All-cause death
413 (6.7%)
All-cause hospitalization
1730 (27.9%)
CV hospitalization
735 (11.8%)
Recurrent MI
234 (3.8%)
Incident heart failure (HF) within 3 months of discharge (no history of HF)
1160 (23.8%)
Incident HF with ejection fraction (EF) < 40%, 41-49%, >50%
42.2%, 26.7%, 31.1%

Observational data: associations, not effects.

Further findings

Death and hospitalizations in patients who developed HF

Higher risk of death and hospitalizations with incident HF, irrespective of EF
all P < .001

EF > 50% without prevalent HF or HF during index hospitalization (n = 2179) · 1 year

Developed HF
257 (11.8%)
Recurrent MI
77 (3.5%)

Original publication

Incident heart failure and recurrent coronary events following acute myocardial infarction. Eur Heart J. Published 28 January 2025. doi:10.1093/eurheartj/ehae885

Summarised from the published abstract; every number is checked against it