Incident Type 2 Myocardial Infarction in a Cohort of Patients Undergoing Coronary or Peripheral Arterial Angiography
Authors' conclusion
T2MI is common and associated with poor prognosis.
Study context
- Population
- Patients undergoing coronary or peripheral angiography with or without intervention
- Participants
- 1,251 patients
- Exposure
- T2MI vs no T2MI
- T2MIn = 152
- Outcome
- Incident T2MI, and subsequent MACE (all-cause death, nonfatal MI, HF, stroke, TIA, peripheral arterial complication, cardiac arrhythmia)
- Follow-up
- Median 3.4 years
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Incident T2MI and subsequent events (per 100 person-years) · median 3.4 years
T2MI
12.2%
152
No T2MI
- Major adverse cardiovascular events (MACE)
- 21.1 per 100 person-years
- All-cause death
- 3.3 per 100 person-years
- CV death
- 2.6 per 100 person-years
- HF events
- 7.4 per 100 person-years
T2MI vs No T2MIAdjusted hazard ratio (95% CI)P value
MACE
1.90(1.46–2.48)
P < 0.001All-cause death
2.96(2.01–4.36)
P < 0.001CV death
2.16(1.36–3.43)
P = 0.001Observational data: associations, not effects.
Further findings
Multivariable predictors of T2MI
- Older age, lower SBP, history of CAD, HF, COPD, DM, nitrate use, elevated glucose, NT-proBNP and cystatin C
Original publication
Incident Type 2 Myocardial Infarction in a Cohort of Patients Undergoing Coronary or Peripheral Arterial Angiography. Circulation. Published 21 November 2016. doi:10.
Summarised from the published abstract; every number is checked against it