Cardiometabolic & kidney

Income variability and incident cardiovascular disease in diabetes: a population-based cohort study

Eur Heart JPublished Population-based cohort study

Main finding · Composite CVDResult — go to the resultHazard ratio 1.25 95% CI 1.22–1.27

Authors' conclusion

Higher income variability, income declines, and sustained low income were associated with increased CVD risk.

Study context

Population
Adults aged 30–64 with T2D and no history of cardiovascular disease (CVD), Korean National Health Insurance Service database, 2009–2012
Participants
1,528,108 adults
Exposure
Highest vs lowest quartile of income variability
Outcome
Composite of:
  • Incident fatal
  • Nonfatal CVD (MI, HF and stroke)
Follow-up
Mean 7.3 years
Methodological detailsnationally representative
  • Nationally representative

Main finding

Composite CVD

Hazard ratio

1.25

95% CI 1.22–1.27

P < 0.001 for trend

Highest quartilevs Lowest quartile
HR 1.25 (95% CI 1.22–1.27); P for trend < 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)P value
Sustained low income (lowest quartile) over 5 yearsn = 5 yearsvs n = 0 years1.38 (1.35–1.41)P for trend < 0.0001
Sustained high income (highest quartile) over 5 yearsn = 5 yearsvs n = 0 years0.71 (0.70–0.72)P for trend < 0.0001

Income decline (4 years ago vs baseline)

Increased CVD risk, particularly when income decreased to the lowest level (Medical Aid), regardless of initial income

Original publication

Income variability and incident cardiovascular disease in diabetes: a population-based cohort study. Eur Heart J. Published 26 April 2024. doi:10.1093/eurheartj/ehae132

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