HypertensionCohort study
Individual and joint effects of red blood cell traits on hypertension: a longitudinal analysis
- Prospective cohort study
- longitudinal
- sex-stratified
Authors' conclusion
Our findings suggest that RBC count primarily plays a role in women's hypertension, while hemoglobin mainly affects hypertension in men.
Study context
- Population
- Adults from the Kailuan CohortKailuan Cohort
- Participants
- 51,663 adults
- Exposure
- Red blood cell (RBC) count and hemoglobin categories, individually and jointly
- Outcome
- New-onset hypertension
Main finding
As reported in the abstract
New-onset hypertension, joint effects by sex
Each group vs RBC (-) and hemoglobin (-)Hazard ratio (95% CI)
RBC (+) and hemoglobin (-)women; not in men
1.19(1.02–1.39)
RBC (-) and hemoglobin (+)men; not in women
1.12(1.06–1.18)
Observational data: associations, not effects.
Further findings
Sensitivity and cross-sectional analyses
- Findings consistent in sensitivity and cross-sectional analyses
Original publication
Individual and joint effects of red blood cell traits on hypertension: a longitudinal analysis. Eur J Prev Cardiol. Published 21 February 2025. doi:10.1093/eurjpc/zwaf093
Summarised from the published abstract; every number is checked against it