Acute cardiac care & resuscitationTrial design
Individualized Or Conventional Transfusion Strategy During Veno-Arterial Extracorporeal Membrane Oxygenation Support (ICONE Study): Rationale and Design of a Prospective Multicenter Randomized Controlled Trial
- multicenter, randomized, controlled trial
- stratified according to postcardiotomy versus medical etiology
- rationale and design; currently recruiting
Study context
- Population
- Adult patients supported by veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for refractory cardiogenic shockplanned sample size
- Participants
- 236 patients
- Planned comparison
- individualized or conventional transfusion strategy
- Primary endpoint
- number of red blood cell (RBCs) units transfused per day of ECMO support
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Individualized Or Conventional Transfusion Strategy During Veno-Arterial Extracorporeal Membrane Oxygenation Support (ICONE Study): Rationale and Design of a Prospective Multicenter Randomized Controlled Trial. Am Heart J. Published 28 September 2026. doi:10.1016/j.ahj.2026.107616
Summarised from the published abstract; every number is checked against it