Integrating Dietary Inflammatory Index and Triglyceride-Glucose Body Mass Index for Mortality Association in Hypertension
Authors' conclusion
DII and TyG-BMI are significant indices that may enhance personalized strategies for CVD prevention and management.
Study context
- Population
- Hypertensive adults (≥18 years), NHANES 2001 to 2018
- Participants
- 8,024 adults
- Exposure
- Proinflammatory diet and elevated TyG-BMI, individually and jointly
- Outcome
- CVD and all-cause mortality
- Follow-up
- Median 9.91 years
Main finding
As reported in the abstract
Hazard ratio (95% CI)
Proinflammatory dietCVD mortality
1.36(1.00–1.85)
Proinflammatory dietall-cause mortality
1.29(1.08–1.54)
Elevated TyG-BMICVD mortality
1.46(1.10–1.94)
Elevated TyG-BMIall-cause mortality; not statistically significant
1.12(0.96–1.32)
High DII + high TyG-BMICVD mortality
1.98(1.33–2.94)
Observational data: associations, not effects.
Further findings
Cardiovascular disease (CVD) mortality, men (subgroup)
| Comparison | HR (95% CI) | |
|---|---|---|
| Men | 2.15 (1.27–3.63) | |
| 0.20.5125Hazard ratio (log scale) |
| Outcome | HR (95% CI) | |
|---|---|---|
| CVD mortality, adults ≥60 years (subgroup)High DII + low TyG-BMI vs Low DII + middle TyG-BMI · highest CVD risk in this subgroup | 1.91 (1.41–2.59) | |
| 0.20.5125Hazard ratio (log scale) |
Original publication
Integrating Dietary Inflammatory Index and Triglyceride-Glucose Body Mass Index for Mortality Association in Hypertension. JACC Adv. Published 12 November 2025. doi:10.
Summarised from the published abstract; every number is checked against it