Arrhythmias & electrophysiologyCohort study
Integration of Functional Mapping and Image-Guided Structural Information in Ventricular Tachycardia Ablation - Sense2 Mapping
- prospective multicenter registry
- propensity score-matched
Authors' conclusion
Sense2 protocol, integrating imaging with functional mapping, reduced procedural times by enabling focused substrate mapping to be performed and improved outcomes in terms of VT freedom compared with Institutional ablation. The improved survival requires corroboration with multicenter randomized trials.
Study context
- Population
- Patients with post-infarct ventricular tachycardia (VT)patients enrolled
- Participants
- 166 patients
- Exposure
- Sense2 vs Sense vs Institutional
Main finding
As reported in the abstract
Mean procedural time
- Significantly shorter in the Sense2 group
- P < 0.0001
Observational data: associations, not effects.
Further findings
Ablation time
Mean, minutes
| Outcome | Sense2 | Sense | Institutional |
|---|---|---|---|
| Mean mapping time | 25.4 (SD 7.3) | 47.2 (SD 8.9) | Not reported in the abstract |
- Ablation time — Significantly reduced in the Sense2 group
- P = .006
Mean mapping time
- Shorter in the Sense2 group
Freedom from VT
- Higher in Sense2 and Sense groups than Institutional group
- P < 0.001 for both
Survival
- Improved in Sense2 and Sense groups than Institutional group
- P < 0.05 for both
Original publication
Integration of Functional Mapping and Image-Guided Structural Information in Ventricular Tachycardia Ablation - Sense2 Mapping. Heart Rhythm. Published 4 September 2026. doi:10.1016/j.hrthm.2026.07.054
Summarised from the published abstract; every number is checked against it