Prevention & lipidsResearch article
Interactions of Obstructive Sleep Apnea With the Pathophysiology of Cardiovascular Disease, Part 1
- Narrative review
Study context
- Population
- Patients with obstructive sleep apnea (OSA)
Main finding
As reported in the abstract
Interactions of OSA with CVD pathophysiology
- OSA associated with repetitive altered blood gases, arousals, large negative intrathoracic pressure swings and increased sympathetic activity
- OSA associated with altered gut microbiota, which could contribute to increased CVD risk
- OSA associated with hypertension, AF, HF, CAD, stroke and excess CV mortality
- OSA with chronic obstructive lung disease (overlap syndrome) or morbid obesity (obesity hypoventilation syndrome) increases odds of mortality
Original publication
Interactions of Obstructive Sleep Apnea With the Pathophysiology of Cardiovascular Disease, Part 1. J Am Coll Cardiol. Published 24 September 2024. doi:10.1016/j.jacc.2024.02.059
Summarised from the published abstract; every number is checked against it