Coronary disease & ACSCohort study

Intracoronary Imaging Implementation Gap in Contemporary Percutaneous Coronary Intervention (PCI)

JACC AdvPublished

  • prospective, multicenter study
  • consecutive patients
  • 23 Italian imaging-capable centers

Authors' conclusion

Even in imaging-capable centers, intracoronary imaging remains underused in anatomically complex PCI. This implementation gap appears driven predominantly by operator attitudes and intersite practice variation rather than by cost or technical barriers alone. (Barriers Limiting OCT Penetration in Clinical Practice [OCT2ACT]; NCT07193693).

Study context

Population
Consecutive patients undergoing PCI across Italian imaging-capable centers between September 15 and December 15, 2025consecutive patients enrolled
Participants
1,189 patients
Exposure
cohort 1 vs cohort 2 vs cohort 3

Main finding

As reported in the abstract

No intracoronary imaging among patients meeting predefined class IA criteria

Patients meeting predefined class IA criteria

908

of whom did not undergo intracoronary imaging

481 (53.0%)

Observational data: associations, not effects.

Further findings

Outcomecohort 1cohort 2cohort 3
Imaging modality
IVUSNot reported in the abstract72%Not reported in the abstract
optical coherence tomographyNot reported in the abstractNot reported in the abstract54%
  • Imaging modality: in cohort 3 mainly for diagnostic clarification in ambiguous acute coronary syndromes or stent failure

Barriers to imaging use

Angiography considered sufficient or imaging judged unlikely to change PCI strategy (operator-reported attitudinal factors)
278 patients (57.8%)

Imaging uptake across centers

Range of imaging uptake across centers
16.7% to 100.0%

Original publication

Intracoronary Imaging Implementation Gap in Contemporary PCI. JACC Adv. Published 17 July 2026. doi:10.1016/j.jacadv.2026.102982

Summarised from the published abstract; every number is checked against it