Aortic & peripheral vascular diseaseSecondary analysis
Intraluminal vs Subintimal Drug-Coated Balloon Angioplasty for the Treatment of Femoropopliteal Chronic Total Occlusions
- Secondary analysis of the POPCORN registry
- propensity-score matched
- multicentre
- prospective registry
Authors' conclusion
The present study revealed that intraluminal DCB angioplasty was superior to subintimal DCB angioplasty for FP CTO treatment, with a significantly better 1-year rate of freedom from restenosis.
Study context
- Population
- Symptomatic patients with lower extremity artery disease and femoropopliteal chronic total occlusion (CTO) treated with drug-coated balloon
- Participants
- 469 lesions
- Comparison
- Subintimal vs intraluminal drug-coated balloon (DCB) angioplasty
- Primary endpoint
- Freedom from restenosis
- Follow-up
- 1 year
Primary result
As reported in the abstract
P = 0.024
Further findings
Restenosis during follow-up (whole cohort) · median follow-up 14.2 months
- Patients with restenosis
- 140
Restenosis risk with subintimal DCB angioplasty, by subgroup (interaction analysis)
- More marked increased restenosis risk with subintimal DCB angioplasty in severe calcification, low-dose DCB use or smoking
Original publication
Intraluminal vs Subintimal Drug-Coated Balloon Angioplasty for the Treatment of Femoropopliteal Chronic Total Occlusions. JACC Cardiovasc Interv. Published 11 March 2024. doi:10.1016/j.jcin.2023.12.028
Summarised from the published abstract; every number is checked against it