Aortic & peripheral vascular disease
Intraluminal vs Subintimal Drug-Coated Balloon Angioplasty for the Treatment of Femoropopliteal Chronic Total Occlusions
Authors' conclusion
The present study revealed that intraluminal DCB angioplasty was superior to subintimal DCB angioplasty for FP CTO treatment, with a significantly better 1-year rate of freedom from restenosis.
Study context
- Population
- Symptomatic patients with lower extremity artery disease and femoropopliteal chronic total occlusion (CTO) treated with drug-coated balloon
- Participants
- 469 lesions
- Comparison
- Subintimal vs intraluminal drug-coated balloon (DCB) angioplasty
- Primary endpoint
- Freedom from restenosis
- Follow-up
- 1 year
Methodological detailspropensity-score matched, multicentre, prospective registry
- Propensity-score matched
- Multicentre
- Prospective registry
Primary result
As reported in the abstract
P = 0.024
Further findings
Restenosis during follow-up (whole cohort) · median follow-up 14.2 months
- Patients with restenosis
- 140
Restenosis risk with subintimal DCB angioplasty, by subgroup (interaction analysis)
- More marked increased restenosis risk with subintimal DCB angioplasty in severe calcification, low-dose DCB use or smoking
Original publication
Intraluminal vs Subintimal Drug-Coated Balloon Angioplasty for the Treatment of Femoropopliteal Chronic Total Occlusions. JACC Cardiovasc Interv. Published 11 March 2024. doi:10.
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