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HypertensionTrial design

Investigating Endogenous Hypercortisolism Prevalence in a U.S. Population With Resistant Hypertension

JACC AdvPublished

  • observational, multicenter study
  • large
  • first
  • United States
Read the original article ↗

Study context

Population
Adults aged ≥18 years with resistant hypertension (rHTN) defined by American Heart Association criteria, in the United Statestarget enrollment
Participants
approximately 1,000 adults
Primary endpoint
Endogenous hypercortisolism prevalence (cortisol level >1.8 μg/dL on the 1-mg overnight dexamethasone suppression test with adequate dexamethasone (≥140 ng/dL))

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Investigating Endogenous Hypercortisolism Prevalence in a U.S. Population With Resistant Hypertension. JACC Adv. Published 16 February 2026. doi:10.1016/j.jacadv.2026.102596
Read the original article ↗PubMedCite RIS · BibTeX

Summarised from the published abstract; every number is checked against it