Heart failure & cardiomyopathies
Iron Deficiency and Incident Heart Failure in Older Community-Dwelling Individuals
Main finding · Incident HFResult — go to the resultHazard ratio 1.47 CI 1.02–2.11Authors' conclusion
Among community-dwelling elders, iron deficiency is independently associated with incident HF, an association that was similar irrespective of CKD status.
Study context
- Population
- Community-dwelling adults aged ≥65 years without heart failure (HF) (41% with chronic kidney disease (CKD)), Cardiovascular Health Study414 total HF cases
- Participants
- 1,006 adults
- Exposure
- Iron status categories vs iron replete
- Outcome
- Incident HF
Methodological detailsweighted Cox models
- Weighted Cox models
Main finding
As reported in the abstract
Hazard ratio
1.47
CI 1.02–2.11
Iron deficiencyvs Iron replete
HR 1.47 (CI 1.02–2.11)
Observational data: associations, not effects.
Further findings
Incident HF with iron deficiency, by CKD status (subgroup)
- Relationship did not differ by CKD status
- interaction P value 0.2
Original publication
Iron Deficiency and Incident Heart Failure in Older Community-Dwelling Individuals. ESC Heart Fail. Published 26 February 2024. doi:10.
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