Prevention & lipidsCohort study
Joint association of physical activity and sleep duration with risk of all-cause and cause-specific mortality: a population-based cohort study using accelerometry
- Prospective cohort study
- population-based
- accelerometry
Authors' conclusion
MVPA meeting recommendations or a higher volume of PA at any intensity potentially diminished the adverse effects on all-cause and cause-specific mortality associated with short and long sleep duration.
Study context
- Population
- UK Biobank participants with 7-day accelerometer recording, 2013–20153,080 deaths
- Participants
- 92,221 participants
- Exposure
- Combinations of moderate-to-vigorous PA (MVPA) and sleep duration
- Outcome
- All-cause and cause-specific (CVD, cancer) mortality
- Follow-up
- Median 7.0 years
Main finding
As reported in the abstract
All-cause mortality
Each group vs recommended MVPA + normal sleepHazard ratio (95% CI)
No recommended MVPA + short sleep
1.88(1.61–2.20)
No recommended MVPA + long sleep
1.69(1.49–1.90)
- Physical activity (PA) and sleep duration had additive and multiplicative interactions on mortality risk
- P for interaction < 0.05
- Curvilinear dose-response associations of PA and sleep duration with mortality
- Pnonlinearity <0.001
Observational data: associations, not effects.
Further findings
All-cause and cardiovascular disease (CVD) mortality
- Higher PA volume or recommended MVPA attenuated the detrimental effects of short or long sleep
- 1074 CVD deaths; 1871 cancer deaths
Original publication
Joint association of physical activity and sleep duration with risk of all-cause and cause-specific mortality: a population-based cohort study using accelerometry. Eur J Prev Cardiol. Published 29 March 2023. doi:10.1093/eurjpc/zwad060
Summarised from the published abstract; every number is checked against it