Pulmonary vascular disease & thromboembolism

Key elements of follow-up care after acute pulmonary embolism focusing on long-term sequelae: a Delphi study among European experts

Eur Heart J Qual Care Clin OutcomesPublished Delphi study

Authors' conclusion

This Delphi study among a panel of VTE experts across Europe describes a consensus-based framework for structured follow-up care for PE-survivors, emphasizing the need for a standardized, multidisciplinary approach to detecting long-term sequelae of PE.

Study context

Population
Venous thromboembolism (VTE) experts from across Europe, on follow-up care of pulmonary embolism (PE) survivors39 completed both rounds
Participants
45 experts
Outcome
Expert consensus on PE follow-up care
Methodological details2 survey rounds, multidisciplinary European expert panel
  • 2 survey rounds
  • Multidisciplinary European expert panel

Main finding

As reported in the abstract

  • Follow-up should address the entire spectrum of post-PE sequelae (chronic thrombo-embolic pulmonary hypertension (CTEPH), chronic thromboembolic pulmonary disease, all other presentations of post-PE syndrome)
  • Routine assessment at 3 months should involve patient-reported outcome measures, incl. quality of life
  • A single, uniform protocol preferred over locally adapted approaches
  • Earlier follow-up (before 3 months) not considered necessary for most patient subgroups
  • Right heart catheterization to confirm CTEPH reserved for specialized pulmonary hypertension centres; CT, V/Q scan, cardiopulmonary exercise testing and transthoracic echocardiography can be performed in non-referral centres

Observational data: associations, not effects.

Original publication

Key elements of follow-up care after acute pulmonary embolism focusing on long-term sequelae: a Delphi study among European experts. Eur Heart J Qual Care Clin Outcomes. Published 1 July 2025. doi:10.1093/ehjqcco/qcaf053

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