Heart failure & cardiomyopathiesMeta-analysis
Knowledge About Self-Efficacy and Outcomes in Patients with Heart Failure and Reduced Ejection Fraction
- Pooled analysis of individual patient data from three randomised clinical trials
Authors' conclusion
Poor patient-reported 'self-efficacy' may be associated with higher rates of mortality.
Study context
- Population
- Patients with heart failure and reduced ejection fraction (HFrEF) enrolled in three recent clinical trials3 trials
- Comparison
- Poor vs fair vs good self-rated knowledge of self-management
- Outcome
- Primary composite outcome, by self-rated knowledge (poor, moderate, good)
Pooled result
As reported in the abstract
Primary composite outcome, rate per 100 person-years (95% CI)
| Group | Prevention question | Response question |
|---|---|---|
| Poor | 12.83 (12.11-13.60) | 12.88 (12.13-13.67) |
| Fair | 12.08 (11.53-12.65) | 12.22 (11.60-12.86) |
| Good | 11.55 (11.00-12.12) | 11.56 (11.07-12.07) |
Further pooled results
| Outcome | Poor | Fair | Good |
|---|---|---|---|
| Distribution of self-rated knowledge | |||
| Prevention | 4197 (23.8%) | 6897 (39.1%) | 6535 (37.1%) |
| Response | 4033 (22.9%) | 5463 (31.0%) | 8141 (46.2%) |
Components: CV and all-cause death, HF hospitalization
- Lower event rates with 'good' knowledge accounted for by lower CV (and all-cause) death, not HF hospitalization
Patient characteristics
- 'Poor' knowledge: older, more often female, worse HF profile, similar treatment
Original publication
Knowledge About Self-Efficacy and Outcomes in Patients with Heart Failure and Reduced Ejection Fraction. Eur J Heart Fail. Published 26 July 2023. doi:10.1002/ejhf.2944
Summarised from the published abstract; every number is checked against it