Coronary disease & ACS

Distal Radial Access for Coronary Procedures in a Large Prospective Multicenter Registry: The KODRA Trial

JACC Cardiovasc IntervPublished Prospective multicentre registry

Authors' conclusion

In this large-scale prospective multicenter registry, DRA demonstrated high success rates of CAG and PCI, with a high rate of puncture success but low rates of distal radial artery occlusion, radial artery occlusion, bleeding events, and procedure-related complications. Weak pulse and DRA experience <100 cases were predictors of puncture failure.

Study context

Population
Patients undergoing coronary angiography or percutaneous coronary intervention (PCI) via distal radial access, 14 Korean hospitals, September 2019 – September 20215,712 screened
Participants
4,977 patients
Outcome
Success rates of coronary angiography (CAG) and PCI
Methodological details14 hospitals
  • 14 hospitals

Main finding

As reported in the abstract

Procedural success via DRA
GroupCoronary angiography (CAG) successPCI success
Distal radial access (DRA)100%98.8%

Distal radial access (DRA)

Coronary angiography (CAG) success100%
PCI success98.8%

Observational data: associations, not effects.

Secondary outcomes

Predictors of puncture failure (multilevel logistic regression)

ComparisonOR (95% CI)
Weak pulse9.994 (7.252–13.774)
DRA experience <100 cases2.187 (1.383–3.456)

Successful distal radial artery puncture

Puncture success
94.4%

Access-site crossover

Access-site crossover, 333 patients
6.7%

Safety

OutcomeValues
Distal radial artery occlusion and radial artery occlusion (by palpation) · 1-month follow-upDRA Distal radial artery occlusion 0.8% (36 of 4,340) · Radial artery occlusion 0.8% (33 of 4,340)
DRA-related bleeding eventsDRA 3.3%

DRA-related bleeding events

No serious hematoma

Original publication

Distal Radial Access for Coronary Procedures in a Large Prospective Multicenter Registry: The KODRA Trial. JACC Cardiovasc Interv. Published 12 February 2024. doi:10.1016/j.jcin.2023.11.021

Summarised from the published abstract; every number is checked against it

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