Valvular & structural heart disease
Leaflet Splitting to Prevent TAVR-Induced Coronary Obstruction in Stented vs Stentless Surgical Bioprosthetic Valves
Authors' conclusion
BASILICA is technically feasible for both stented and stentless valves. However, stentless valves had a higher rate of partial CAO after BASILICA and TAVR and may therefore require additional or alternative coronary artery protection measures in selected patients.
Study context
- Population
- Patients undergoing BASILICA and valve-in-valve transcatheter aortic valve replacement (TAVR), EURO-BASILICA registryEURO-BASILICA registry
- Participants
- 131 patients
- Exposure
- Stented vs Stentless
- Stentedn = 115reference
- Stentlessn = 16
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Target leaflet-related CAO
Target leaflet-related CAO
Partial, non-flow-limiting CAO
P < 0.001
- Stentless vs Stented: P < 0.001 — target leaflet-related coronary artery obstruction (CAO)
Observational data: associations, not effects.
Further findings
Leaflet length
P < 0.001
Contrast medium
P < 0.001
Fluoroscopy time
P = 0.023
Leaflet length
- Risk for CAO comparable
Fluoroscopy time
- Trend toward longer procedure time with stentless valves
Safety
In-hospital complications, 30-day outcomes, late CAO and MI · 1-year follow-up
- In-hospital complications and 30-day outcomes similar
- No late CAO or MI during 1-year follow-up
Original publication
Leaflet Splitting to Prevent TAVR-Induced Coronary Obstruction in Stented vs Stentless Surgical Bioprosthetic Valves. JACC Cardiovasc Interv. Published 8 June 2026. doi:10.
Summarised from the published abstract; every number is checked against it