Arrhythmias & electrophysiology
Left Atrial Appendage Occlusion Under Miniaturized Transesophageal Echocardiographic Guidance and Conscious Sedation: Multicenter European Experience
Authors' conclusion
LAAO under conscious sedation and miniaturized TEE guidance is safe and feasible with a high rate of technical success and a low rate of periprocedural complications.
Study context
- Population
- Left atrial appendage occlusion (LAAO) procedures performed under miniaturized transesophageal echocardiography (TEE) guidance and conscious sedation
- Participants
- 546 consecutive procedures
- Outcome
- Technical success
Methodological detailsmulticentre, 5 European centres, consecutive procedures
- Multicentre
- 5 European centres
- Consecutive procedures
Main finding
As reported in the abstract
Technical success
534
98.0%
Observational data: associations, not effects.
Secondary outcomes
Technical success by device-sizing imaging
P < 0.001
- Technical success by device-sizing imaging: preprocedural 3-dimensional vs procedural 2-dimensional imaging for device sizing
Procedural success (technical success without major periprocedural complications)
- Procedural success rate
- 97.0%
Short-term imaging follow-up
- Major (>5 mm) TEE-detected residual leaks
- 0.7%
- Complete LAA occlusion on cardiac CT
- 82.2%
- Device-related thrombus
- 5%
- Imaging follow-up available in 422 patients
Conversion to general anaesthesia
- Conversion to general anesthesia required
- 4 (0.7%)
Safety
Major periprocedural complications
- Sixteen major periprocedural complications in 15 patients
- 15 (2.9%)
Conversion to general anesthesia
- Conversion to general anesthesia
- 4 (0.7%)
Original publication
Left Atrial Appendage Occlusion Under Miniaturized Transesophageal Echocardiographic Guidance and Conscious Sedation: Multicenter European Experience. JACC Cardiovasc Interv. Published 14 August 2023. doi:10.
Summarised from the published abstract; every number is checked against it