Arrhythmias & electrophysiology
Left Atrial Function Predicts Atrial Arrhythmia Recurrence Following Ablation of Long-Standing Persistent Atrial Fibrillation
Authors' conclusion
Following ablation for long-standing persistent AF, improvement in LA function was greater in those who maintained sinus rhythm. LA contractile strain at 3 months was the most important determinant of AF recurrence following ablation.
Study context
- Population
- Patients undergoing catheter or surgical ablation of de-novo long-standing persistent atrial fibrillation (AF)with analysable echo data
- Participants
- 83 patients
- Comparison
- Sinus rhythm vs AF recurrence after ablation
- Sinus rhythmn = 30
- AF recurrencen = 53reference
Methodological detailsEchocardiography preablation, 3 and 12 months post-ablation; continuous rhythm monitoring by implantable loop recorder
- Echocardiography preablation, 3 and 12 months post-ablation; continuous rhythm monitoring by implantable loop recorder
Primary result
As reported in the abstract
LA function at 3 months
| Group | Left atrial (LA) emptying fraction | Reservoir strain | Contractile strain |
|---|---|---|---|
| Sinus rhythm | 36.3±10.6% | 22.6±8.5% | 9.2±3.4% |
| AF recurrence | 27.9±9.9% | 16.7±5.7% | 5.6±2.5% |
Left atrial (LA) emptying fraction
Sinus rhythm36.3±10.6%
AF recurrence27.9±9.9%
Reservoir strain
Sinus rhythm22.6±8.5%
AF recurrence16.7±5.7%
Contractile strain
Sinus rhythm9.2±3.4%
AF recurrence5.6±2.5%
- Sinus rhythm vs AF recurrence: P < 0.001 — LA emptying fraction
- Sinus rhythm vs AF recurrence: P = 0.001 — reservoir strain
- Sinus rhythm vs AF recurrence: P < 0.001 — contractile strain
Further findings
| Outcome | Sinus rhythm | AF recurrence | P value |
|---|---|---|---|
| Diastolic functionE/e' ratio | P < 0.001 | ||
| E/A ratio | 1.5±0.5 | 2.2±1.2 | P < 0.001 |
| LV E/e' ratio | 8.0±2.1 | 10.3±4.1 |
Original publication
Left Atrial Function Predicts Atrial Arrhythmia Recurrence Following Ablation of Long-Standing Persistent Atrial Fibrillation. Circ Cardiovasc Imaging. Published 8 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →