Heart failure & cardiomyopathies
Left ventricular electrical delay predicts volumetric response to leadless cardiac resynchronization therapy
Primary result · LVESV response (reduction >15%)Result — go to the resultAdjusted odds ratio 1.015Authors' conclusion
Increased Q-LV was associated with improved reverse remodeling following leadless CRT.
Study context
- Population
- Patients in the active arms of SOLVE-CRT receiving leadless left ventricular (LV) endocardial cardiac resynchronization therapy (CRT) (WiSE-CRT system)of 153 with complete Q-LV data
- Participants
- 122 patients
- Comparison
- LV pacing site Q-LV and left ventricular end-systolic volume (LVESV) response to leadless CRT
- Primary endpoint
- LVESV reduction >15%
- Follow-up
- 6 months
Methodological detailspost hoc analysis
- Post hoc analysis
Primary result
LVESV response (reduction >15%)
Adjusted odds ratio
1.015
P = 0.05
By group
As reported in the abstract
- Overall 6-month LVESV response rate
- 46%
Further findings
| Outcome | Adjusted OR | P value |
|---|---|---|
| LVESV response, ischemic cardiomyopathy (subgroup) · 6 months | 1.034 | P = 0.004 |
Original publication
Left ventricular electrical delay predicts volumetric response to leadless cardiac resynchronization therapy. Heart Rhythm. Published 28 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →